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Tablet Friability Test Procedure

Friability Testing measures the potential percent weight loss of compressed tablets by replicating the rigorous environmental conditions that tablets are subjected to during the manufacturing, packaging, and distribution processes. Tablets need to be hard enough not to break up in the bottle but friable enough that they disintegrate in the gastrointestinal tract.

In a friability test, samples are counted and weighed, then tumbled in the rotating drums with baffles. Friability is determined when the process is stopped by weighing the samples again and calculating the difference between the before and after weight. Friability should not exceed 1%, which is considered the ideal percentage.